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DrYak

@dryak@mstdn.science
  • Open on mstdn.science

Medical Doctor and Bioinformatician

446 Followers
547 Following
50 Posts
Joined November 14, 2022
ORCiD:
https://orcid.org/0000-0002-7561-0810
GitHub:
https://github.com/DrYak

Posts

Open post
dryak
DrYak @dryak@mstdn.science · Jul 16, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @aeva@mastodon.gamedev.place
@aeva@mastodon.gamedev.place followed shortly by "Microsoft Visual P#". (subtly not compatible with CPython; locks you irreversibly into the .NET ecosystem)
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dryak
DrYak @dryak@mstdn.science · Jul 13, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @keisatsu@infosec.exchange
@keisatsu@infosec.exchange @jschauma@mstdn.social Meanwhile, the rate of glue-eating related emergency hospitalisations has mysteriously sunken at the exact same time as that outage.
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dryak
DrYak @dryak@mstdn.science · Jul 10, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @ck0@tech.lgbt
@ck0@tech.lgbt @soatok@furry.engineer Regarding not being dependent on the whims of a single central org: Cwtch seems promising as it is completely decentralized over the Tor network and aims for good e2ee. Regarding Signal: they seem to have calmed down with kickban - I have been daily driving using Whisperfish as the primary app and no problem since a year.
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dryak
DrYak @dryak@mstdn.science · Jul 04, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @Tutanota@mastodon.social
@Tutanota@mastodon.social (and: Android -> SailfishOS)
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dryak
DrYak @dryak@mstdn.science · Jun 11, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @rasterweb@mastodon.social
@rasterweb@mastodon.social No love for Puyo-puyo? 🥺
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Open post
dryak
DrYak @dryak@mstdn.science · Jun 08, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @eladnarra@disabled.social

@eladnarra@disabled.social @ifixcoinops@retro.social hence the "mostly".

Though:

  • they aren't CLI by necessity, it should be possible to wrap a nice GUI around (just like the countless existing GUI that wrap around cd burning and ripping tools, ffmpeg, etc.)
  • there are WISIWYG markdown editors
  • Git isn't required. Some registrars (e.g. Infomaniak) offer a tiny static website that you can SFTP into (with FileZilla) to deposit you static files.

The building block are here.

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Open post
dryak
DrYak @dryak@mstdn.science · Jun 08, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @ifixcoinops@retro.social
@ifixcoinops@retro.social sideway tangeant, (from someone who did start with writing tags in a texf editor and was listening to the rationale behind CSS): I am under the impression that static website generators that ingest Markdown and spit out stuff that you can upload on the hosting that came for free with the domain you registeted, did mostly got us "there".
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Open post
dryak
DrYak @dryak@mstdn.science · Jun 07, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @musevg@23.social
@musevg@23.social @cstross@wandering.shop @aral@mastodon.ar.al @s10n@mastodon.social @matt@oslo.town was wondering the same, and managed to keyword-search a source [link deleted, @denisbloodnok@mendeddrum.org 's reply bellow is better] Yes, it looks like a nornal bottle opener. The key part here is not the bottle opener end, but the pointy bit at the opposite end: you can use it to stab cans open (I would guess in a similar fashion as the sharp hook on a swiss knife can opener when you start?)
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dryak
DrYak @dryak@mstdn.science · May 17, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @TechTangents@dialup.space
@TechTangents@dialup.space ...and the saddest part is that Google is the least bad option among the email-blocking cartel. (Outlook 365, I am looking at you!) I am extremely lucky that I don't need to run my own domain's e-mails through the cartel, but my use-case is rather the exception...
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dryak
DrYak @dryak@mstdn.science · May 16, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @redhorsesec@fosstodon.org
@redhorsesec@fosstodon.org @da_667@infosec.exchange (Re: army barracks Now add poor hand hygiene while mostly outdoor, and now you also have a higher rate of gastro intestinal infections on top. Both all year round with no seasons (respiratory even in summer, and gastro int. even in winter). I absolutely DO NOT miss my mandatory military service as an army doctor. At least hopefully on the ship they wash their hands properly and miss out on that half of the fun...)
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dryak
DrYak @dryak@mstdn.science · May 16, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @hacks4pancakes@infosec.exchange
@hacks4pancakes@infosec.exchange ever considered switching carreers and going into academics to write software to hunt evil viruses? (speaking from personnal experience)
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dryak
DrYak @dryak@mstdn.science · May 12, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @flesh@transfem.social
@flesh@transfem.social ...and then don't forget to #PushToProdFriday
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dryak
DrYak @dryak@mstdn.science · May 12, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @MicroSFF@mastodon.art
@MicroSFF@mastodon.art on a side note, Sleepless Domain had the reverse situation: an AMAB whose transness get outted when they suddenly gain the capability to transform into a magical girl warior, which in that universe comes with a constantly visible mark even when not transformed.
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dryak
DrYak @dryak@mstdn.science · May 12, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @HauntedOwlbear@eldritch.cafe
@glassresistor@sfba.social @HauntedOwlbear@eldritch.cafe oh, that's indeed an interesting new standard: https://en.wikipedia.org/wiki/Auracast ! I wonder if it would be possible to retro-fit into headphones with community firmware (e.g. @pine64@social.treehouse.systems 's Pinebuds Pro)
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dryak
DrYak @dryak@mstdn.science · May 12, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @SRLevine@neuromatch.social
@SRLevine@neuromatch.social @HauntedOwlbear@eldritch.cafe yup, nowadays you would need to order them from AliExpress and the likes. Super cheap but... Slow! No way to get an emergency replacement the day before you leave for a road trip, it's a multi-days wait situation.
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dryak
DrYak @dryak@mstdn.science · May 12, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @dryak@mstdn.science
@HauntedOwlbear@eldritch.cafe am sure the manufacturers' official excuse is something along the line of Bluetooth standards not offering some simple way to do synchronization (there is nothing like "PTP over Bluetooth") and therefore music sounds weird when broadcast to multiple receivers which don't support the same proprietary extensions. (which would actually not be a hard requirement to share music on _headsets_. But "lock-in / network effect" are to too juicy profit sources)
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dryak
DrYak @dryak@mstdn.science · May 12, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @HauntedOwlbear@eldritch.cafe
@HauntedOwlbear@eldritch.cafe The worst part: it's actually possible, a lot of headphones allow it... But only using some weird proprietary extension, only from the official app(*), and only among devices within the same manufacturer(**). It's as if you needed to buy one of those 80s' splitter for each separate brand of wired headphones. 🤮 (*): kudos to Logitech to allow this with only buttons presses, no app required. (**): am sure some noname on AliExpress forgot to put limitations and might cross pair.
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Open post
dryak
DrYak @dryak@mstdn.science · May 11, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @stonebear2@hachyderm.io
@stonebear2@hachyderm.io @VeroniqueB99@mastodon.social Litteraly happen to our HPC some time ago(*): the whole data centre starts over heating, then safety trips and nodes gets shutdown in an uncoordinated brown-out. (*: because of a isolated powerloss in the pumping system, without engaging backup, while the cluster isn't powered by backup). In our science cluster, it merely was a mess to restart. In badly designed/hastily built AI data centres, the servers cook themselves, hw is damaged.
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dryak
DrYak @dryak@mstdn.science · May 10, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @dryak@mstdn.science
@rrustema020@mastodon.nl @erwinrossen@mas.to [...] Though knowing big tech: google will certainly find their own creative way to misclassify workers, and somehow the hardware loss will be entirely the responsibility of the poor underpaid and overworked "human supervisor" (aka 3rd world remote operator).
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dryak
DrYak @dryak@mstdn.science · May 10, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @rrustema020@mastodon.nl
@rrustema020@mastodon.nl @erwinrossen@mas.to oh, I am sure some will find very creative way to disturb the cars, and "Have the thing autonomously go for a swim" will certainly be one of those. (While being classified as art/happening in Germany). But depending on the city, I was more thinking along the lines of: "You think google has anything to say if a waymo gets surrounded by a dozen of angry cyclists?". [...]
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dryak
DrYak @dryak@mstdn.science · May 10, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @rrustema020@mastodon.nl
@rrustema020@mastodon.nl @erwinrossen@mas.to Yup. In serveral European country the whole thing would rapidly turn into a large scale experiment in trying to determine how many waymos you can pile on top of each other at the bottom of a cannal.
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dryak
DrYak @dryak@mstdn.science · May 10, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @dryak@mstdn.science

@Luk@mamot.fr [...]

  • personnel inadapte (le superviseur de l'atelier d'esclavage en asie qui ne parle meme pas francais et jette juste un oeuil qu'il y ait les memes lettres d'alphabet latin que sur le bon de commande)

...

  • et oui, et aussi un PDG de boite qui n'en a rien carree tant qu'il continue d'engranger des bonus en auto-recompense pour toutes les economies realisees sur tous les autres de la chaine.
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dryak
DrYak @dryak@mstdn.science · May 10, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @Luk@mamot.fr

@Luk@mamot.fr je pense que "ces gens qui n'en ont rien a carree" est un melange de:

  • informatique toute pourrie sans la moindre supervision humaine (genre scripts vibe-code avec le cul, "agents" ia, etc.)

  • main d'oeuvre complement sous payee et sur exploitee (genre un pauvre gars en outre-mer paye 50cts d'Euro a la jpurnee et qui a un quota de 200 commandes a validater par heure a faire, sous peine de perdre son boulot (et devoir rembourser sa "formation")

[...]

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dryak
DrYak @dryak@mstdn.science · May 08, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @mathieu_@eldritch.cafe
@mathieu_@eldritch.cafe @AudeCaussarieu@social.sciences.re fondamentalement, les AI generatives fonctionnent a l'echelle des pixels d'une image (ou video), et n'ont pas vraiment un model abstrait d'une scene (pas de plan 3D en tete) C'est pour ca aussi sur les model plus vieux les doigts surnumeraires, les 3e mains mal placees, etc. Meme-si ces erreures la sont plus facilement corrigibles.
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dryak
DrYak @dryak@mstdn.science · May 08, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @dryak@mstdn.science
@kai_klnd@troet.cafe @Tutanota@mastodon.social Most recently AI - What's the point in encrypting everything end-to-end and then have the end-point stream all messages back to cloud servers running Meta's AI for summarising, "smart"-search and othe similar useless crap? So yeah that E2EE is very "on paper theoretically", and in practice is mostly a marketing ploy to gain some user confidence avoid them switching, in the years after the scandals around Snowden blowing the whistle.
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dryak
DrYak @dryak@mstdn.science · May 08, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @kai_klnd@troet.cafe
@kai_klnd@troet.cafe @Tutanota@mastodon.social surpisingly: yes, mostly since reorganizing its direct messaging feature to rely on Facebook Messenger, which it self had incorporated the E2EE protocol from Signal, not long after doing the same with WhatsApp. Though "E2E" is very relative - technically such scheme can only be trusted as much as said end-points - which is hard given than none of the Apps by Meta are open source. And all these apps have a few extremely glaring holes: ...
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dryak
DrYak @dryak@mstdn.science · May 08, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @dryak@mstdn.science
@SciTania@scicomm.xyz Update, c'est là: https://virological.org/t/complete-sequence-of-orthohantavirus-andesense-virus-swiss-resident-2026/1023
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dryak
DrYak @dryak@mstdn.science · May 08, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @dryak@mstdn.science
@SciTania@scicomm.xyz En tout cas notre équipe suit cela attentivement et nous nous tenons tou.te.s prêt.e.s s'il faudra étendre les programmes de surveillances si les autorités viennent vers nous dans quelque temps. (Ajouter des cibles aux eaux usées, voir ressusciter le séquençage de masse)
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dryak
DrYak @dryak@mstdn.science · May 08, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @SciTania@scicomm.xyz
@SciTania@scicomm.xyz > si peu de cas Oui, tout à fait: si on a de la chance, les 8 ou 9 cas actuelements connus sont à eux seuls l'intégralité de ce cluster. Ce qui m'inquiète (surtout que l'HPS causé par le Hanta des amériques est en deux phases, et que la première ressemble juste à un gros refroidissement), c'est que peut-être on n'est au courant que des cas les plus symptomatiques et que ça ait beaucoup plus circulé sur le bateau et donc eu l'opportunité de muter et s'adapter.
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dryak
DrYak @dryak@mstdn.science · May 08, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @dryak@mstdn.science
@SciTania@scicomm.xyz Update de collègues de collègues de Genève: ça devrait arriver sur virological [dot] org plus tard aujourd'hui.
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dryak
DrYak @dryak@mstdn.science · May 08, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @davidtheeviloverlord@mastodon.social
@davidtheeviloverlord@mastodon.social @TrevfromIreland@mastodon.ie @Pinchy63@ottawa.place Well, the glasses should be still banned from public spaces, and people with disabilities who need them(*) as aids get special exemptions wutg glasses clearly marked so. See the precedent set by, e.g., guide dogs in spaces where pets wouldn't be allowed. (*): though the best would be to have properly regulated dedicated medical devices, not to repurpose the pricacy violating toys of some tech billionaire
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dryak
DrYak @dryak@mstdn.science · May 07, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @SciTania@scicomm.xyz
@SciTania@scicomm.xyz Exactement! La transmissibilité est à déterminer à partir des données observées épidémiologiquement, en traçant les cas, déterminant le R, etc. On ne pourra effectivement pas prédire grand chose à partir de mutations sur les séquences des prélèvement sur les infectés. La plus part des mutations seront inconnues au bataillon sur Uniprot. Il n'y pas (encore) de base référence de "mutations cliniquement relevantes".
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dryak
DrYak @dryak@mstdn.science · May 07, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @dryak@mstdn.science
@SciTania@scicomm.xyz Normalement, si je ne me trompe pas, les collegues a Geneve devraient bientot publier les data sur ENA, Pathoplexus, plateforme nationale, etc. (perso, la question que je me pose c'est si ces quelques semaines avec 270 personnes dans la meme boite en metal a donne suffisament de "passages" au virus de ce cluster pour qu'il ameliore sa transmissibilite humain-a-humain par rapport a la base pas tres folichon des H. Andensis).
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dryak
DrYak @dryak@mstdn.science · May 07, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @SciTania@scicomm.xyz
@SciTania@scicomm.xyz L'un des patients est traite chez nous en Suisse (a Zurich), et les authorites ont confirme le Hantavirus. (https://www.swissinfo.ch/eng/various/man-with-hantavirus-is-being-treated-at-zurich-university-hospital-switzerland/91371503 https://www.admin.ch/en/newnsb/p--A7yPSfxdBqR0N9kZMC) souche Andensis (labo a Geneve: https://www.hug.ch/en/actualite/hantavirus-outbreak-cruise-ship-hug-have-identified-strain-virus)
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dryak
DrYak @dryak@mstdn.science · May 06, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @dantheclamman@scicomm.xyz
@dantheclamman (...and suddenly, all people who encounter boosts/who follow you from accounts bridged from other networks that use algorithmic auto moderation [e.g. Threads, Blusky, etc.] start to feel nervous...)
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dryak
DrYak @dryak@mstdn.science · May 05, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @hrefna@hachyderm.io
@hrefna wait until you discover that the drop list for "sex" was also automatically lifted from Wikipedia and in addition to usual "male/female/nonbinary/prefere not to say" it also contains 137 different mating types of fungi.
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dryak
DrYak @dryak@mstdn.science · May 02, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @Tutanota@mastodon.social

@Tutanota @edri Missing: in the Android category please also consider alternatives which are not derivatives of AOSP (of the open source parts or android), i.e. mobile GNU/Linux distros such as:

  • SailfishOS
  • PostmarketOS
  • UbuntuTouch etc.

SFOS is definitely daily driveable: I am posting from a phone running it.

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dryak
DrYak @dryak@mstdn.science · May 01, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @abranson@mastodon.social
@abranson@mastodon.social that's cool! Hopefully there'll be a way in the future to properly register Tooter-Beta as a handler of the URLs. (any way to show notifications _in the feed_, as opposed to currently as pop-ups?)
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dryak
DrYak @dryak@mstdn.science · Apr 26, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @AimeeMaroux@mastodon.social
@AimeeMaroux Yes, and in addition of that "bus drivers" isn't even a profession that is in dire need of AI replacement to begin with. I.e.: it's only disadvantages (as you point out), no real advantage (It's called *mass*-transit for a reason. Over a whole year, there's a metric crap ton of people riding public transport. The salary of the drivers are a tiny drop in the bucket of the cost to operate the transportation network. AI won't save that much money per ride).
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dryak
DrYak @dryak@mstdn.science · Apr 25, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @alda@topspicy.social
@alda @dermoth @hailey They were by passing indeed. Picoprocess: process creation is heavy weight on Windows, so Microsoft had to implement picoprocesses in the kernel on which WSL1 could rely.
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dryak
DrYak @dryak@mstdn.science · Apr 23, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @SuperSelena64@vmst.io
@SuperSelena64@vmst.io infinite battery life!
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dryak
DrYak @dryak@mstdn.science · Apr 11, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @AndrewRadev@hachyderm.io
@AndrewRadev Yes, exactly : As if AI needed any active intervention, be it by GenZers or anyone else, to sabotage itself...
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dryak
DrYak @dryak@mstdn.science · Apr 11, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @dryak@mstdn.science
@ZachWeinersmith (I am sure you'll manage before recess)
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dryak
DrYak @dryak@mstdn.science · Apr 11, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @ZachWeinersmith@mastodon.social
@ZachWeinersmith > "POOF, a rotation matrix appears" Next step: quaternions.
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dryak
DrYak @dryak@mstdn.science · Apr 09, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @kaflurbaleen@mastodon.social
@kaflurbaleen does the generative-kitten function also works with cups on Linux?
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dryak
DrYak @dryak@mstdn.science · Apr 03, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @thom@swiss.social
@thom@swiss.social is there some popular initiative against we could sign?
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dryak
DrYak @dryak@mstdn.science · Apr 02, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @Tock@corteximplant.com
@Tock @geerlingguy note that the oligopolists fanning this greedflation are exactly counting on such a rush to buy. The best would be to ask one self whether you really need these electronics with those specs, or whether you could fall back on lower specs, second hand, or entirely skip the upgrade. (less money going into the pockets of 3 Ram makers quasimonopolies)
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dryak
DrYak @dryak@mstdn.science · Apr 02, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @RonsCompVids@bitbang.social
@RonsCompVids @geerlingguy ...and you can add "unregulated quasi-monopolies being ultra greedy" to the list (e.g. 3 RAM makers dominating the markets and fixing prices, yet again).
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dryak
DrYak @dryak@mstdn.science · Apr 02, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @geerlingguy@mastodon.social
@geerlingguy I am lucky that I managed to snatch a 16GB CM5 for my Argon one up before!
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dryak
DrYak @dryak@mstdn.science · Mar 26, 2026
DrYak
@dryak@mstdn.science

Medical Doctor and Bioinformatician

mstdn.science
Replying to @eloquence@social.coop
@eloquence@social.coop Specially since Deepseek's approach of publishing good research papers, releasing the model, and making smaller models that one can locally goes contrary to the trend in the USA to be very secretive about models themselves, and pretend the only way forward is crazy large models that must be run in bonkers expensive continent-spanning datacenters in a giant arms' race.
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