#pasc

Tom Kindlon @tomkindlon@disabled.social · 5d ago

Boosted by

From the Netherlands Wearable Heart Rate Variability Monitoring, Autonomic Dysfunction and Post-exertional Malaise in Long COVID: An Observational Study https://link.springer.com/article/10.1007/s40279-026-02487-4 Screenshot from latest Science for ME weekly update @longcovid@fedigroups.social #LongCovid #PASC #PwLC #postcovid #postcovid19 #PostCovidSyndrome #LC #Covidlonghaulers #longhaulers #HRV #MEcfs #PwME #CFS #ME #MyalgicE @mecfs@fedigroups.social

3

0

7

0

datum (n=1) @datum@zeroes.ca · Aug 01, 2026

Even if a complete neuron doesn't die, if a huge chunk of the synapses are destroyed, whatever that neuron was doing before, it's doing a fraction afterwards: a measurable, consistent, and symptom-correlated loss of dopamine nerve terminals averaging 18 percent across the long COVID group. with localized damage to areas that match Long COVID symptoms: “In other illnesses this magnitude of loss is associated with symptoms: loss in one region is associated with trouble with motivational energy problems, loss in another region is associated with some slowness of movement, and loss in a third region is associated with memory trouble.” in short, the terminals are gone, the loss is measurable, and it correlates with the symptoms patients have been reporting for years. https://tech-paper.com/scientists-finally-have-a-biological-explanation-for-why-long-covid-patients-lose-motivation-and-cant-think-clearly-they-scanned-their-brains-and-found-the-dopamine-system-was-physically-damaged/ #neuroscience #neurology #science #LongCOVID #PASC #health

42

0

54

0

Tom Kindlon @tomkindlon@disabled.social · Jul 30, 2026

From Germany 🇩🇪 Cerebral gray matter volumes in long-term post-COVID patients are associated with peripheral kynurenine pathway metabolites and the severity of depressive symptoms https://www.sciencedirect.com/science/article/abs/pii/S0889159126006665 Screenshot from Science for ME weekly update #LongCovid #COVIDBrain #NeuroPASC #postcovid #PASC #PwLC #postcovid19 #PostCovidSyndrome @longcovid@fedigroups.social

1

0

3

0

datum (n=1) @datum@zeroes.ca · Jul 20, 2026

Researchers tested undergrads while measuring brain blood flows. Their brain scans looked like people in their 60s: previously infected students exhibited distinct prefrontal haemodynamic patterns during cognitive engagement, reminiscent of those observed in adults four decades older, and this appeared to be especially true if they reported experiencing brain fog due to COVID-19. Over a third of them showed objective cognitive impairment: 37.33 % of participants who reported previously having COVID-19 displayed objective cognitive impairment [...] (assessed via computerised testing), And neuron death is irreversible: This may indicate microglial hyperactivation, theoretically driven by elevated oxidative stress from dysfunctional mitochondria—a possible contributor to cell death and cognitive impairment https://www.sciencedirect.com/science/article/pii/S0889159124007311 h/t @PatrickWirth@mstdn.ca #COVID #SARSCoV2 #LongCOVID #COVID19 #BrainFog #PASC

1

0