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@jonobie@social.coop

Post #1215618

2026-04-16 12:43 UTC

An absolutely fascinating writeup about Advil (ibuprofen), Tylenol (acetaminophen, paracetamol), and which painkiller is better and why. With a brief sidebar ode to past FDA science: https://asteriskmag.com/issues/14/the-mystery-in-the-medicine-cabinet

Replies (7)

  • @bouriquet@mastodon.social 2026-04-16 12:57

    @jonobie It seems that anything that messes with your liver chemistry will have severe consequences in your body. That’s also my issue with statins and many other drugs. They generally have more than just the desired effect on the liver. There are also other effects that have negative consequences. There is no magic pill.

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  • @tiggy@mastodonapp.uk 2026-04-16 13:05

    @jonobie I thought for years that paracetamol had little effect on me. It's true it doesn't help on its own with some of my pain sources (eg migraine, fibromyalgia, etc.) and has a minor effect in working with other painkillers I take. But it turns out it is very good for the pain from my recent eye operation. I can tell when the last dose starts to wear off and how well it works first thing in the morning. Surprising as I'd thought a NSAID would be better

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  • @dlakelan@mastodon.sdf.org 2026-04-16 13:37

    @jonobie For the Europeans what's called Acetaminophen in US is Paracetamol in the EU.

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  • @jonobie CBD is also an anti-inflammatory

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  • @perigee@rage.love 2026-04-16 15:02

    @jonobie thanks for the link. Now I know why I'm warned off nsaids beyond just "you have kidney disease".

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  • @elithebearded@fed.qaz.red 2026-04-16 21:09

    @jonobie I have avoided this problem by taking aspirin for pains whenever I can. Also I don't trust myself to remember which one has the liver risk, and take the one that once treated as the ideal medicine except for stomach irritation. Would have been interesting to see a similar treatment of aspirin versus those two

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  • @Oaktag@infosec.exchange 2026-04-17 14:08

    @jonobie Quite interesting! For my headaches tylenol does nothing, but it might help with body aches so I'll reach for it more

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