Lupposofi
@Lupposofi@mementomori.social
Olin tieteenfilosofi ja tietoteoreetikko. Opetin kriittistä ajattelua yliopistossa. (Re)tired. Ihmettelen elämää lähinnä Lupposofina (ks. kotisivu), ja ajoittain yhä opin. Vältän pönkittämästä uutismedian luomaa ja ylläpitämää ajan tasaa. Seurailemiani sivustoja: https://plato.stanford.edu/new.html https://informallogic.ca/index.php/informal_logic https://social-epistemology.com/ https://philosophyofbrains.com/ https://www.alzforum.org/all-news https://bios.fi/#blogi https://journal.fi/
mementomori.social
Bart De Strooper presented at the Copenhagen AD/PD-conference an excellent sketch of the three main inflection points in the pathophysiological evolution of Alzheimer's disease, https://www.alzforum.org/news/conference-coverage/big-picture-three-inflection-points-mark-amyloid-cascade
My own transition from amyloid plagues to p-tau and tangles was retarded by a four years' anti-amyloid therapy in a clinical reaearch project during 2017-22 (aducanumab). Sadly, the most probable explanation for my rapidly worsening cognitive problems may indeed be the tau-tangles, which I somehow avoided earlier. I know there are experimental therapies around somewhere for those gremlins too, but sadly not within my own reach. With respect to my AD, I'm afraid, it's "too late, my friend".
I encourage anybody with a slowly lethal disease to keep mentally in touch with it as long as you can. That's what we human beings were made for. 🤗
#alzheimer #ad #at #disease #medical #amyloid #tau #lethal #sairaus #alzForum #realism #humanity #reflection #thinking #dying #terminallyill #metacognition #tietoisuus #consciousness