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Tim Fallon, PhD

@photocyte@genomic.social
mastodon 4.6.6
  • Open on genomic.social

biologist, biochemist, genomics enthusiast, bioinformatician, roboticist, natural products disciple. MIT PhD. Current postdoc in the Moore lab @ SIO/UCSD https://photocyte.github.io

#biology #biochemistry #bioluminescence #evolution #genomics #bioinformatics #cheminformatics #semanticweb #wikidata #biosynthesis #algae

Twitter: @photocyte@genomic.social

337 Followers
411 Following
8 Posts
Joined November 25, 2022
🌍 WEBSITE:
https://photocyte.github.io
🎓 ORCID:
https://orcid.org/0000-0002-3048-7679
PRONOUNS:
he/him/his

Posts

Open post
photocyte
Tim Fallon, PhD @photocyte@genomic.social · Oct 28, 2024
Tim Fallon, PhD
@photocyte@genomic.social

biologist, biochemist, genomics enthusiast, bioinformatician, roboticist, natural products disciple. MIT PhD. Current postdoc in the Moore lab @ SIO/UCSD https://photocyte.github.io #biology #biochemistry #bioluminescence #evolution #genomics #bioinformatics #cheminformatics #semanticweb #wikidata #biosynthesis #algae Twitter: @photocyte

genomic.social
Replying to @photocyte@genomic.social
@jonny@neuromatch.social Still working on this suprisingly! (our server's storage has been acting up, so many retries on downloads) Do you know any existing example of an automated pipeline to download, do some ETL type things, build a derived database, and then publish it to bittorrent & a simple website? This is a common pattern in bioinformatics. There are a lot of moving parts there, and while I could come up with it, would be helpful if someone already navigated...
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Open post
photocyte
Tim Fallon, PhD @photocyte@genomic.social · Oct 17, 2024
Tim Fallon, PhD
@photocyte@genomic.social

biologist, biochemist, genomics enthusiast, bioinformatician, roboticist, natural products disciple. MIT PhD. Current postdoc in the Moore lab @ SIO/UCSD https://photocyte.github.io #biology #biochemistry #bioluminescence #evolution #genomics #bioinformatics #cheminformatics #semanticweb #wikidata #biosynthesis #algae Twitter: @photocyte

genomic.social
Replying to @jonny@neuromatch.social
@jonny@neuromatch.social Thanks! Okay, I gave Linux CLI bittorrent clients a quick google, and picked Transmission as that seems still developed vs rtorrent , and claimed a CLI client, but in looking into it in more depth the CLI clients seem deprecated? What do you use? Looking for something that would allow Linux CLI for finding & downloading or publishing a given file via low-friction (trackerless / DHT? / Zeroconf / mDNS ) approaches.
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Open post
photocyte
Tim Fallon, PhD @photocyte@genomic.social · Oct 14, 2024
Tim Fallon, PhD
@photocyte@genomic.social

biologist, biochemist, genomics enthusiast, bioinformatician, roboticist, natural products disciple. MIT PhD. Current postdoc in the Moore lab @ SIO/UCSD https://photocyte.github.io #biology #biochemistry #bioluminescence #evolution #genomics #bioinformatics #cheminformatics #semanticweb #wikidata #biosynthesis #algae Twitter: @photocyte

genomic.social
Replying to @photocyte@genomic.social
@jonny@neuromatch.social See also: the 194 GB "Reference_Proteomes_2024_05.tar.gz" from https://ftp.ebi.ac.uk/pub/databases/uniprot/current_release/knowledgebase/reference_proteomes/
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Open post
photocyte
Tim Fallon, PhD @photocyte@genomic.social · Oct 14, 2024
Tim Fallon, PhD
@photocyte@genomic.social

biologist, biochemist, genomics enthusiast, bioinformatician, roboticist, natural products disciple. MIT PhD. Current postdoc in the Moore lab @ SIO/UCSD https://photocyte.github.io #biology #biochemistry #bioluminescence #evolution #genomics #bioinformatics #cheminformatics #semanticweb #wikidata #biosynthesis #algae Twitter: @photocyte

genomic.social

Hey @jonny@neuromatch.social I'm running into very typical pain point of having to download huge files in bioinformatics (almost 1 TB Kraken2 index). Although they are available "instantly" on public clouds, distributed downloading globally and distributed sharing internally would be really neat (or at least, a simple solution to point people towards versus just centralizing it all on a shared filesystem).

What's your recommended tool for doing this? Good ole bittorrent?

File example:
https://github.com/BenLangmead/aws-indexes?tab=readme-ov-file

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Open post
photocyte
Tim Fallon, PhD @photocyte@genomic.social · Aug 10, 2024
Tim Fallon, PhD
@photocyte@genomic.social

biologist, biochemist, genomics enthusiast, bioinformatician, roboticist, natural products disciple. MIT PhD. Current postdoc in the Moore lab @ SIO/UCSD https://photocyte.github.io #biology #biochemistry #bioluminescence #evolution #genomics #bioinformatics #cheminformatics #semanticweb #wikidata #biosynthesis #algae Twitter: @photocyte

genomic.social

@failedLyndonLaRouchite@mas.to @cmdcolin@genomic.social @ScienceMagazine@press.coop

Doesn't happen every day! All credit to the algae for having simultaneously novel and interpretable giant enzymes. Based on this preprint, titin takes ~6 hours to translate, and spontaneous frameshift (and translational aborition) probability during this lengthy translation gets almost expected.

So P. parvum definitely work hard to make their PKZILLAs!

https://www.biorxiv.org/content/10.1101/2024.04.08.588516v1

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Open post
photocyte
Tim Fallon, PhD @photocyte@genomic.social · Aug 09, 2024
Tim Fallon, PhD
@photocyte@genomic.social

biologist, biochemist, genomics enthusiast, bioinformatician, roboticist, natural products disciple. MIT PhD. Current postdoc in the Moore lab @ SIO/UCSD https://photocyte.github.io #biology #biochemistry #bioluminescence #evolution #genomics #bioinformatics #cheminformatics #semanticweb #wikidata #biosynthesis #algae Twitter: @photocyte

genomic.social
Replying to @cmdcolin@genomic.social
@cmdcolin@genomic.social @ScienceMagazine@press.coop Your help played a part! Really appreciate it, I can't remember exactly where I used it, perhaps the modules on the genomic coordinates in Fig S6 , S7. It's called somewhere in the Zenodo items though... https://genomic.social/@cmdcolin/112100755859796058
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Open post
photocyte
Tim Fallon, PhD @photocyte@genomic.social · Aug 08, 2024
Tim Fallon, PhD
@photocyte@genomic.social

biologist, biochemist, genomics enthusiast, bioinformatician, roboticist, natural products disciple. MIT PhD. Current postdoc in the Moore lab @ SIO/UCSD https://photocyte.github.io #biology #biochemistry #bioluminescence #evolution #genomics #bioinformatics #cheminformatics #semanticweb #wikidata #biosynthesis #algae Twitter: @photocyte

genomic.social

It came from the deep(ish) ocean... and then transitioned to a euryhaline lifestyle causing widespread fish-killing blooms in brackish water throughout Texas and Europe... It's Prymnesium parvum and their #PKZILLA s! Out today in @ScienceMagazine@press.coop https://www.science.org/doi/10.1126/science.ado3290

genomic.social

genomic.social

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Open post
photocyte
Tim Fallon, PhD @photocyte@genomic.social · Mar 15, 2023
Tim Fallon, PhD
@photocyte@genomic.social

biologist, biochemist, genomics enthusiast, bioinformatician, roboticist, natural products disciple. MIT PhD. Current postdoc in the Moore lab @ SIO/UCSD https://photocyte.github.io #biology #biochemistry #bioluminescence #evolution #genomics #bioinformatics #cheminformatics #semanticweb #wikidata #biosynthesis #algae Twitter: @photocyte

genomic.social
Replying to @oritpeleg@mastodon.social
@oritpeleg Have you contacted Larry Buschman? He might be in Colorado but either way would be a good person to relay this through. I've also forwarded it to my Colorado firefly network ;)
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