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@Mepurfield@autistics.life

Post #918471

2026-04-03 15:51 UTC

Regulatory T cells (Tregs) altered in children with autism "Tregs act as immune system "brakes," calming inflammation to prevent overreaction. They are often decreased in autistic individuals." https://www.eurekalert.org/news-releases/1122657 #actuallyautistic

Replies (4)

  • @irina@wandering.shop 2026-04-03 15:56

    @Mepurfield ... in mice. Also I object to the term "healthy" to mean "not autistic".

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  • @cesarpose@infosec.exchange 2026-04-03 16:01

    @Mepurfield Perhaps that's why we are more prone to autoimmune diseases. In my family there are already 6 of us diagnosed with autism, 2 girls and 4 adults, and all 4 adults have autoimmune diseases. I have seen the same pattern in my patients.

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  • @Mepurfield . I think a link seems intuitive, but I suppose the pathologization is in, “altered.” . Altered from what, did these kids have normal T-cells before, like before they were born or conceived? Why the leap from “different,” to “altered?”

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  • @hanscees@ieji.de 2026-04-03 21:59

    @Mepurfield Apparently there is a lot of research into the mia hypothesis: that inflammatory processes in the motherof a child during pregnancy can highten chances on #autism. This study sums up the evidenin 2025 Maternal Immune Activation and Autism Spectrum Disorder: https://www.sciencedirect.com/science/article/pii/S0006322324017608 Conclusions and Future Directions In some maternal conditions associated with inflammation—infections, autoimmunity, and high BMI—we have noted a general pattern in the literature in which studies across populations have described associations between these exposures during pregnancy and children’s later likelihood of autism. As more rigorous methods have been incorporated and results have been triangulated (145,146) across approaches, we have seen substantial evidence that the relationship between maternal infections during pregnancy, elevated maternal BMI, and most maternal autoimmune conditions are likely confounded to some degree by shared familial factors So the evidence is not conclusive or false. #actuallyautistic

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