Post #2637935
2026-05-10 13:10 UTC
What is so exciting about PROTACs is they can be designed to destroy almost protein, so their usefulness isn’t limited to cancer therapies, there are PROTACs in the works for neurodegenerative diseases and autoimmunity.
It’s really an amazing time to be in bioscience (there’s bad stuff happening to the scientific enterprise esp in the US but I’ll leave this thread mainly positive)
🧵/end
Replies (2)
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@MCDuncanLab@mstdn.social 2026-05-10 13:34
Funny related story. When I was a postdoc, I wanted a quicker way to inhibit the protein I was studying. We had been using something called temperature sensitive mutations, which were slow or we could have used a regulated promoter, which was also slow.
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@epicdemiologist@wandering.shop 2026-05-10 13:50
@MCDuncanLab@mstdn.social Oh my god, if we could send them after prions!!!