Post #2637936
2026-05-10 13:34 UTC
Funny related story. When I was a postdoc, I wanted a quicker way to inhibit the protein I was studying. We had been using something called temperature sensitive mutations, which were slow or we could have used a regulated promoter, which was also slow.
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@MCDuncanLab@mstdn.social 2026-05-10 13:35
I came up with this amazing idea of using the cell quality control system to rapidly destroy my protein. I was super excited and I talked to somebody who worked on the quality control system, and shared my idea. She asked so like the system that Ray Deshaise is working on? And I realized that I had seen a talk a year or two earlier where Ray had described the system and I had forgotten it and taken it as my own idea.