Post #1986541
2026-04-29 04:36 UTC
Replies (1)
-
@mediaevalfishsandwich@zeroes.ca 2026-04-29 05:59
@datum 🙏 …and thanks to Nitter for the double gloved ability to dig through the posts of those who remained over there. The most Ab-evasive variant will preferentially infect those w/stronger Ab immunity. That was a real "aha!" moment for me, as of course the poor old kids in classrooms have had more chances to develop antibodies than anyone else, and they got hit hard and often early in the pandemic, so may have imprinted on those While my attention span holds, I'm just digging through old stuff, antigenic cartography for BA.3.2. BA.3.2 is off on its own, a long way from those early variants, so the classroom derived antibodies aren't so relevant to defending against it. Whereas adults who may have kept up with boosters, or not so many infections early on, may be better prepared. (As in that JN.1 derived cluster is a lot closer to BA.3.2, although not that close.) https://www.biorxiv.org/content/10.1101/2025.04.30.651462v1.full.pdf