I have an Nvidia GPU and Debian’s latest Nvidia driver update is aproximately one year and a half late in comparison with Nvidia’s latest release. That’s probably the main issue and the reason Debian and LMDE (and some other non-gaming focused distros) don’t work for me (just in the gaming and video editing aspect), so I’m definitely discarding them as gaming (and related) single OS’s atm, though if I could I would run Debian as my main and single OS in my PC.