@tomkindlon@disabled.social I'm currently trying 6 mg melatonin for GERD; it seems to be helping - hope it continues to improve. https://todayspractitioner.com/wp-content/uploads/2015/10/0708_werbach-1.pdf ~ There are reports of melatonin content varying a lot from what is on the label - mostly much higher than what is on the label. Apparently, melatonin can degrade, so some supplement makers put in more to account for its degradation over time: https://youtu.be/0NnAYGM6gF8?si=epB2uv8NsrwQtRw8&t=204 ~ There's evidence from studies on rodents that melatonin can improve blood-brain barrier function: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0154427 If brain inflammation is driving chronic pain, then it seems plausible that melatonin could help.