Post #3588557
2026-05-19 09:20 UTC
Main difference being that weights trained on complete genome reference keeps on looking toward other distant signals to make a call on current input, while contig level genome reference trained model constantly focuses on immediate signal neighbors more often than not.
Replies (1)
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@naturepoker@genomic.social 2026-05-19 09:21
By the time it gets to layer 18 (the output from which gets fed into direct signal-to-sequence translation CTC), the two models end up with a very different looking output.